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Research

"The science of today is the technology of tomorrow."

Edward Teller

Computational Pathology

Computational Pathology

Data Driven Learning of Cancer Morphology

Highly Multiplexed Imaging

Highly Multiplexed Imaging

Cell Segmentation in High Dimensions

Computational Radiology

Computational Radiology

Crohn's Disease Assessment in MRI

Computational Epigenetics

Computational Epigenetics

Epigenetic Biomarker Design

Grading of Spinalstenosis

Grading of Spinalstenosis

Pain Localization in Spinal MRI

Biomarker Detection

Medical Machine Learning

Machine Learning for Marker Discovery

Software

"We're entering a new world in which data may be more important than software."

Tim O'Reilly

MethMarker

MethMarker

A Java based program to automatically design gene-specific DNA methylation assays. These assays may serve as epigenetic biomarkers in a cohort of samples (DNA sequences from cases and controls).

TMARKER

TMARKER

Assists in cell nuclei counting and staining estimation of pathological immunohistochemical TMA images and whole slide images.

Highly Multiplexed Cell Segmentation

Highly Multiplexed Imaging

Assists in whole cell segmentation of highly multiplexed immunohistochemical TMA images and non-TMA images. The software is implemented in MATLAB R2014a, freely available and user friendly.

About

"There are no shortcuts in evolution."

Louis D. Brandeis

  • September 2015 - present

    Postdoctorial Researcher at MSKCC

    We establish a new center for computational pathology at the Memorial Sloan Kettering Cancer Center, New York, USA, the oldest cancer center in the world. In the lab of Prof. Th. Fuchs, we setup a research environment for the computer aided cancer prediction in large scale.

  • October 2014 - July 2015

    Research Assistant at NEXUS

    NEXUS is a ETH platform for the personalized medical data analysis (genetic, clinic or imagery data). I was responsible to setup the image analysis part and to integrate TMARKER into the setting.

  • May 2014 - August 2015

    Postdoctorial Researcher at ETHZ

    Due to high feedback in research community, we continued the development of TMARKER, a software for automatic cell detection and classification in histological images.

  • April 2014

    PhD. at ETHZ

    I recieved my PhD in 2014 as a member of the machine learning laboratory of Prof. J.M. Buhmann, at the ETH Zurich, Switzerland. Here, I specialized in medical image analysis such as histopathological images and MRI scans.

  • April - November 2008

    Research Assistant at MPI

    I continued my studies in epigenetic DNA biomarkers for glioblastoma at the MPI with Dr. C. Bock.

  • March 2008

    MSc. in Computational Biology

    My Master's studies have been concluded at the MPI Saarbrücken, Germany in the group of Prof. Th. Lengauer, with the development of MethMarker, a DNA methylation biomarker analysis Software.

  • December 2006

    BSc. in Bioinformatics

    I obtained my Bachelor's degree in Bioinformatics from the Saarland University in Saarbrücken, Germany. My Bachelor's thesis at the Center of Bioinformatics explored the genetic diversity of a specific protein in six clonally infected HIV patients, supervised by Dr. T. Sing.


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Publications

See also my Google Scholar profile.